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Danielle Buglak

Graduate Student: Cell Biology and Physiology (2016-present)

Contact: berlindm@email.unc.edu

Education: Washington & Jefferson College, Washington, PA – BA in Cell and Molecular Biology

Research: I am interested in how the nucleus and centrosome regulate cell polarity and cell-cell contacts during angiogenesis. Specifically, my project focuses on the roles of nuclear envelope proteins in endothelial cell function.

Publications:

Buglak DB, Kushner EJ, Marvin AP, Davis KL, Bautch VL. (2020) Excess centrosomes disrupt vascular lumenization and endothelial cell adherens junctions. Angiogenesis. 2020 Nov;23(4), 567–575.

 

HUVEC with decreased SUN1, stained with DAPI (nucleus, blue) and VE-cadherin (cell junctions, white). Image obtained using Olympus FV3000 confocal microscope.

Ruter DL, Liu Z, Ngo KM, X S, Marvin A, Buglak DB, Kidder EJ, Bautch VL (2021). SMAD6 Integrates Endothelial Cell Homeostatic Flow Responses Downstream of Notch. Angiogenesis. 2021 May;24(2):387-398.

Funding:

AHA Predoctoral Fellowship 2019-

Past IVB T32 training grant 2017-2019